Publications

• Geoffrey S. Pitt and Yicheng Long. Mutations of Splicing Regulator RBM20 in Atrial Fibrillation. J Am Coll Cardiol Basic Trans Science. (2024) Feb, 9 (2) 181–184 

• Yicheng Long, Taeyoung Hwang, Anne R Gooding, Karen J Goodrich, Tenaya K Vallery, John L Rinn, Thomas R Cech. Evaluation of the RNA-dependence of PRC2 binding to chromatin in human pluripotent stem cells. bioRxiv. (2023)

• Barutcu, A. Rasim, Yicheng Long, and Mo Motamedi. RNA-Mediated Epigenetic and Transcriptional Regulation. Front Genet. (2022). 

• Katerina Kraft, Kathryn E. Yost, Sedona E. Murphy, Andreas Magg, Yicheng Long, M. Ryan Corces, Jeffrey M. Granja, Lars Wittler, Stefan Mundlos, Thomas R. Cech, Alistair N. Boettiger, and Howard Y. Chang. Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation. Proceedings of the National Academy of Sciences, 119(22), e2201883119 (2022). 

• Yicheng Long and Thomas R. Cech. Targeted mutagenesis in human iPSCs using CRISPR genome-editing tools. Methods DOI: 10.1016/j.ymeth.2021.01.002 (2021).

• Yicheng Long*, Taeyoung Hwang*, Karen J. Goodrich, Anne R. Gooding, John L. Rinn and Thomas R. Cech. RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells. Nature Genetics 52, 931–938. https://doi.org/10.1038/s41588-020-0662-x (2020).

(highlighted in Ivano Mocavini & Luciano Di Croce. RNA closing the Polycomb circle. Nature Genetics 52, 866–867 (2020).)

• Xueyin Wang*, Yicheng Long*, Richard D. Paucek, Anne R. Gooding, Thomas Lee, Thomas R. Cech. Regulation of histone methylation by automethylation of PRC2. Genes & Development 33, 1416-1427 (2019).

• Yicheng Long, Ben Bolanos, Lihu Gong, Wei Liu, Karen J. Goodrich, Xin Yang, Siming Chen, Anne R. Gooding, Karen A. Maegley, Ketan S. Gajiwala, Alexei Brooun, Thomas R. Cech, Xin Liu. Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2. eLife 6, e31558 (2017).

• Yicheng Long*, Xueyin Wang*, Daniel T. Youmans* and Thomas R. Cech. How do lncRNAs regulate transcription. Science Advances 3, eaao2110 (2017).

• Yicheng Long, Maria G. Abad, Erik Olson, Elisabeth Carrillo and Jane E. Jackman. Identification of Distinct Biological Functions for Four 3'-5' RNA Polymerases. Nucleic Acids Research 44, 8395-8406 (2016).

• Yicheng Long and Jane E. Jackman. In vitro substrate specificities of 3'-5' polymerases correlate with outcome of tRNA 5'-editing reactions. FEBS Letters 589, 2124-2130 (2015).

• Heike Betat, Yicheng Long, Jane E. Jackman and Mario Mörl. From end to end: tRNA editing at 5’- and 3’-terminal positions. International Journal of Molecular Sciences 15, 23975-23998 (2014).

• Maria G. Abad, Yicheng Long, R. Dimitri Kinchen, Elinor T. Schindel, Michael W. Gray, and Jane E. Jackman. Mitochondrial tRNA 5’-Editing in Dictyostelium discoideum and Polysphondylium pallidum. J. Biol. Chem 289, 15155-15165 (2014).

• Maria G. Abad, Yicheng Long, Allison Willcox, Jonatha M. Gott, Michael W. Gray and Jane E. Jackman. A role for tRNA(His) guanylyltransferase (Thg1)-like proteins from Dictyostelium discoideum in mitochondrial 5'-tRNA editing. RNA 17, 613-623 (2011).

• Juan Wang, Liying Huang, Jian Li, Qiangwang Fan, Yicheng Long, Ying Li and Bing Zhou. Artemisinin Directly Targets Malarial Mitochondria through Its Specific Mitochondrial Activation. PLoS ONE 5, (2010).

• Juan Wang, Liying Huang, Yicheng Long and Bing Zhou. Effect of mitochondrial permeability transition pore in antimalarial action of artemisinin, Progress In Modern Biomedicine 9, 4006-4009 (2009).

(* equal contribution)